Part, Category. Description, 4-bit Shift Register. Company, ETC. Datasheet, Download datasheet. Quote. Find where to buy. Quote. # Store at. °C. 5-Formylcytosine (5-fC) (D5D4K) Rabbit mAb . as recommended in the antibody product datasheet) in 10 ml primary antibody. Datasheet PDF Download – 4-Bit Shift Register, data sheet.

Author: Fegal Dilkis
Country: Sweden
Language: English (Spanish)
Genre: Health and Food
Published (Last): 19 September 2006
Pages: 142
PDF File Size: 9.20 Mb
ePub File Size: 15.90 Mb
ISBN: 271-4-68622-954-1
Downloads: 13908
Price: Free* [*Free Regsitration Required]
Uploader: Nikocage

(PDF) Datasheet PDF Download – 4-Bit Shift Register

We are committed to providing you with a daatsheet and privacy-friendly website. Background Methylation of DNA at cytosine residues is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting, and mammalian development 1,2.

Have trouble resetting your password? Have you published research involving the use of our products? You will receive an e-mail containing a link to start the recovery procedure within minutes. Please let us know!

Your credentials are incorrect or you are trying to login with a non-existing webshop account. You will receive an e-mail from dtaasheet containing your new password in the coming minutes. The current items in your cart are: Datasgeet, there is an inverse correlation between levels of 5-hmC and histone H3K9 and H3K27 trimethylation, suggesting a role for 5-hmC in gene activation Contact us and we will help you.


If so we’d love to hear about it.

74178 Datasheet

Please select dataasheet country. Additionally, TET proteins can further oxidize 5-hmC to form 5-formylcytosine 5-fC and 5-carboxylcytosine 5-caCboth of which are excised by thymine-DNA glycosylase TDGeffectively linking cytosine oxidation to the base excision repair pathway and supporting active cytosine demethylation 6,7.

Therefore webshop accounts that were only used to view prices have been deleted. The supporting documents available for this product can be downloaded below.

As shown in the graph, the antibody only binds to the oligo containing 5-fC. No need xatasheet login to view prices!

Datasheet Datasheet CST The product is not intended to be used for therapeutic or diagnostic purposes in humans or animals. The same sequence of a base pair DNA fragment was generated by PCR using exclusively unmodified cytosine, 5-methylcytosine 5-mC5-hydroxymethylcytosine 5-hmC5-carboxylcytosine 5-caCor 5-formylcytosine 5-fC.

Many cells and tissues contain very low endogenous levels of 5-fC that may fall below the detection limits of this antibody. Product has been added to your cart.

Cell Signaling Technology 5-Formylcytosine (5-fC) (D5D4K) Rabbit mAb – BIOKÉ

Application References Have you published research involving the 47178 of our products? TET protein-mediated cytosine hydroxymethylation was initially demonstrated in mouse brain and embryonic stem cells 5, 8. The antibody was titrated against a single-stranded DNA oligo containing either unmodified cytosine or differentially modified cytosine 5-mC, 5-hmC, 5-caC, 5-fC.


Please refer to this page. Like most websites, we make use of cookies to track your preferences. Our website shows product prices without login! While 5-fC and 5-caC appear to be short-lived intermediate species, there is mounting evidence showing that 5-hmC is a distinct epigenetic mark with various unique functions 10, Since then this modification has been discovered in many tissues, with the highest catasheet found in the brain 9.

Please create a new account with your shipping and billing details if you would like to be able to order or view your discount. The global level of 5-hmC increases during brain development, and 5-hmC is enriched at promoter regions and poised enhancers.

Find your product

The upper panel shows the antibody only binding to the DNA fragment containing 5-fC, while the lower panel shows the membrane stained with methylene blue.

This product is intended for research purposes only. By proceeding on this website, you agree to the placement of these cookies. Login No need to login to view prices!